xStAx-VHLL TFA

• CAT Number: I040198
• Molecular Formula: C154H244N48O29.xC2HF3O2
• Molecular Weight: 3231.89 (free base)
• Purity: ≥95%

xStAx-VHLL TFA(CAT: I040198) is a potent PROTAC (proteolysis targeting chimera) designed to selectively degrade β-catenin, a central mediator of the Wnt signaling pathway. By promoting β-catenin ubiquitination and proteasomal degradation, xStAx-VHLL TFA achieves sustained suppression of aberrant Wnt signaling, which is implicated in various cancers and developmental disorders. This compound effectively reduces β-catenin levels and exhibits strong pathway inhibition in cellular models. As a valuable chemical tool, xStAx-VHLL TFA enables targeted protein degradation studies and supports the development of novel therapeutic strategies focused on Wnt-driven oncogenesis and stem cell regulation.