Xeruborbactam disodium

• CAT Number: I016157
• CAS Number: 2170848-99-2
• Molecular Formula: C10H8BFNa2O5
• Molecular Weight: 283.96
• Purity: ≥95%
• Synonyms: disodium;(2S,4R)-9-fluoro-5,5-dihydroxy-6-oxa-5-boranuidatricyclo[5.4.0.02,4]undeca-1(7),8,10-triene-8-carboxylate
• InChI: InChI=1S/C10H9BFO5.2Na/c12-7-2-1-4-5-3-6(5)11(15,16)17-9(4)8(7)10(13)14;;/h1-2,5-6,15-16H,3H2,(H,13,14);;/q-1;2*+1/p-1/t5-,6-;;/m1../s1
• InChIKey: RLVWXGRGTAHSCI-BNTLRKBRSA-M
• SMILES: [B-]1([C@@H]2C[C@@H]2C3=C(O1)C(=C(C=C3)F)C(=O)[O-])(O)O.[Na+].[Na+]

Xeruborbactam disodium（Cat No.:I016157）is a broad-spectrum cyclic boronate β-lactamase inhibitor designed to restore the activity of β-lactam antibiotics against resistant bacteria. It inhibits both serine β-lactamases and metallo-β-lactamases, including clinically important carbapenemases such as KPC, NDM, VIM, and OXA variants. The disodium salt form enhances solubility and formulation stability, making it suitable for clinical and research applications. Xeruborbactam is being investigated as a next-generation therapeutic option to combat multidrug-resistant Gram-negative infections, offering a promising tool in antimicrobial research and drug development targeting resistant bacterial pathogens.