For research use only. Not for therapeutic Use.
Windorphen(CAT: M005191) is a selective inhibitor of the Wnt/β-catenin signaling pathway, specifically targeting the C-terminal transactivation domain of β-catenin-1 without affecting β-catenin-2. It functions by disrupting the interaction between β-catenin-1 and the transcriptional coactivator p300, while sparing the closely related coactivator CBP. This selective inhibition allows for fine-tuned modulation of β-catenin-mediated gene transcription, offering a unique approach to studying Wnt pathway dynamics in development, cancer, and stem cell biology. Windorphen is a valuable research tool for dissecting the distinct roles of β-catenin coactivators in transcriptional regulation
| CAS Number | 19881-70-0 |
| Synonyms | (Z)-3-chloro-2,3-bis(4-methoxyphenyl)prop-2-enal |
| Molecular Formula | C17H15ClO3 |
| Purity | ≥95% |
| IUPAC Name | (Z)-3-chloro-2,3-bis(4-methoxyphenyl)prop-2-enal |
| InChI | InChI=1S/C17H15ClO3/c1-20-14-7-3-12(4-8-14)16(11-19)17(18)13-5-9-15(21-2)10-6-13/h3-11H,1-2H3/b17-16+ |
| InChIKey | VNRALGZMXHFBPG-WUKNDPDISA-N |
| SMILES | COC1=CC=C(C=C1)C(=C(C2=CC=C(C=C2)OC)Cl)C=O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
