For research use only. Not for therapeutic Use.
WIC1 (Cat No.: I041148) is a novel small-molecule inhibitor that targets the Wnt/β-catenin signaling pathway, a critical regulator of cell proliferation, differentiation, and stem cell maintenance. By disrupting Wnt pathway activation, WIC1 suppresses β-catenin–mediated transcription, making it a valuable tool for studying cancer, fibrosis, and developmental disorders where Wnt signaling is dysregulated. It aids in the exploration of targeted therapies aimed at modulating Wnt activity. WIC1 is intended for research use only in cellular, molecular, and pharmacological investigations.
| CAS Number | 943083-58-7 |
| Synonyms | N-[4-(4-ethylpiperazin-1-yl)phenyl]-2-oxochromene-3-carboxamide |
| Molecular Formula | C22H23N3O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C22H23N3O3/c1-2-24-11-13-25(14-12-24)18-9-7-17(8-10-18)23-21(26)19-15-16-5-3-4-6-20(16)28-22(19)27/h3-10,15H,2,11-14H2,1H3,(H,23,26) |
| InChIKey | YQXKWSNLAVFZJL-UHFFFAOYSA-N |
| SMILES | CCN1CCN(CC1)C2=CC=C(C=C2)NC(=O)C3=CC4=CC=CC=C4OC3=O |
| Reference | [1]. Brigitte N, et al. Compositions and methods for treating cancer and improving epithelial homeostasis. Patent. WO2021133460A1. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
