For research use only. Not for therapeutic Use.
2-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-3-oxopropyl]isoindole-1,3-dione(CAT: I040347) is a phthalimide-based small molecule featuring a piperazine linker with a terminal hydroxyethyl group. This compound is structurally suited for use as a cereblon (CRBN) E3 ligase-recruiting ligand in the design of PROTACs (proteolysis-targeting chimeras). The phthalimide core mimics thalidomide-like scaffolds, enabling CRBN binding, while the piperazine-linked hydroxyethyl tail provides functional versatility for conjugation to target protein ligands. It is ideal for research in targeted protein degradation, chemical biology, and therapeutic development. Suitable for use in in vitro assay systems and PROTAC assembly workflows.
| CAS Number | 796888-73-8 |
| Synonyms | 2-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-3-oxopropyl]isoindole-1,3-dione |
| Molecular Formula | C17H21N3O4 |
| Purity | ≥95% |
| IUPAC Name | 2-[3-[4-(2-hydroxyethyl)piperazin-1-yl]-3-oxopropyl]isoindole-1,3-dione |
| InChI | InChI=1S/C17H21N3O4/c21-12-11-18-7-9-19(10-8-18)15(22)5-6-20-16(23)13-3-1-2-4-14(13)17(20)24/h1-4,21H,5-12H2 |
| InChIKey | MOWRLPDFNRKQJS-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1CCO)C(=O)CCN2C(=O)C3=CC=CC=C3C2=O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
