For research use only. Not for therapeutic Use.
WAY-639872(CAT: I040596) is a potent, state-dependent inhibitor of the voltage-gated sodium channel NaV1.7, a key target implicated in nociceptive signal transmission and pain perception. By preferentially inhibiting the open or inactivated states of NaV1.7, WAY-639872 effectively suppresses hyperactive neuronal firing associated with pathological pain. It exhibits high selectivity for NaV1.7 over other sodium channel isoforms, minimizing off-target effects. WAY-639872 is a valuable tool for studying pain mechanisms and developing novel analgesic strategies, particularly in conditions such as neuropathic pain, inflammatory pain, and congenital insensitivity to pain syndromes. Suitable for both in vitro and in vivo research applications.
| CAS Number | 796119-18-1 |
| Synonyms | N-(2-morpholin-4-ylphenyl)-2-quinolin-8-yloxyacetamide |
| Molecular Formula | C21H21N3O3 |
| Purity | ≥95% |
| IUPAC Name | N-(2-morpholin-4-ylphenyl)-2-quinolin-8-yloxyacetamide |
| InChI | InChI=1S/C21H21N3O3/c25-20(15-27-19-9-3-5-16-6-4-10-22-21(16)19)23-17-7-1-2-8-18(17)24-11-13-26-14-12-24/h1-10H,11-15H2,(H,23,25) |
| InChIKey | ZJRDHGFMVANNGO-UHFFFAOYSA-N |
| SMILES | C1COCCN1C2=CC=CC=C2NC(=O)COC3=CC=CC4=C3N=CC=C4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
