WAY-354574

• CAT Number: I040490
• CAS Number: 851873-40-0
• Molecular Formula: C20H23ClN2O3S
• Molecular Weight: 406.93
• Purity: ≥95%
• Synonyms: 3-(azepan-1-ylsulfonyl)-N-[(3-chlorophenyl)methyl]benzamide
• InChI: InChI=1S/C20H23ClN2O3S/c21-18-9-5-7-16(13-18)15-22-20(24)17-8-6-10-19(14-17)27(25,26)23-11-3-1-2-4-12-23/h5-10,13-14H,1-4,11-12,15H2,(H,22,24)
• InChIKey: KBOSWQKMRZDVNV-UHFFFAOYSA-N
• SMILES: C1CCCN(CC1)S(=O)(=O)C2=CC=CC(=C2)C(=O)NCC3=CC(=CC=C3)Cl

WAY-354574(CAT: I040490) is a bioactive small molecule that modulates the activity of sirtuin deacetylases, a class of NAD⁺-dependent enzymes involved in cellular stress responses, metabolism, and gene regulation. It has been studied for its therapeutic potential in neurodegenerative disorders, particularly Huntington’s disease (HD), where altered sirtuin activity contributes to disease progression. By influencing sirtuin-mediated deacetylation pathways, WAY-354574 may help restore transcriptional balance and improve neuronal survival. This compound serves as a valuable research tool for exploring the role of sirtuins in epigenetic regulation and neuroprotection. Supplied in high purity, it is suitable for preclinical neuroscience and epigenetics research.

Reference

WAY-354574 is a bioactive small molecule that modulates the activity of sirtuin deacetylases, a class of NAD⁺-dependent enzymes involved in cellular stress responses, metabolism, and gene regulation. It has been studied for its therapeutic potential in neurodegenerative disorders, particularly Huntington’s disease (HD), where altered sirtuin activity contributes to disease progression. By influencing sirtuin-mediated deacetylation pathways, WAY-354574 may help restore transcriptional balance and improve neuronal survival. This compound serves as a valuable research tool for exploring the role of sirtuins in epigenetic regulation and neuroprotection. Supplied in high purity, it is suitable for preclinical neuroscience and epigenetics research.