For research use only. Not for therapeutic Use.
WAY-313318(CAT: I040595) is a selective inhibitor of SIRT1, a NAD⁺-dependent class III histone deacetylase involved in regulating transcription, metabolism, aging, and stress responses. By blocking SIRT1 activity, WAY-313318 enhances acetylation of SIRT1 substrates such as p53 and FOXO transcription factors, enabling detailed exploration of SIRT1-mediated pathways. This compound is a valuable research tool for studying the epigenetic regulation of gene expression and the role of SIRT1 in diseases like cancer, metabolic syndrome, and neurodegeneration. Its selectivity and potency make WAY-313318 suitable for in vitro assays and cellular studies targeting sirtuin biology.
| CAS Number | 351993-88-9 |
| Synonyms | N-(benzotriazol-1-ylmethyl)-2,3-dichloroaniline |
| Molecular Formula | C13H10Cl2N4 |
| Purity | ≥95% |
| IUPAC Name | N-(benzotriazol-1-ylmethyl)-2,3-dichloroaniline |
| InChI | InChI=1S/C13H10Cl2N4/c14-9-4-3-6-11(13(9)15)16-8-19-12-7-2-1-5-10(12)17-18-19/h1-7,16H,8H2 |
| InChIKey | CKZSPQIIOBZZRC-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)N=NN2CNC3=C(C(=CC=C3)Cl)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
