For research use only. Not for therapeutic Use.
WAY-213613 hydrochloride（Cat No.:I046106）is a potent, selective inhibitor of the excitatory amino acid transporter 2 (EAAT2/GLT-1), the predominant glutamate transporter in the central nervous system. By blocking EAAT2, it elevates extracellular glutamate concentrations, making it a valuable tool for studying excitatory neurotransmission, synaptic plasticity, and neurotoxicity. This compound is frequently used in preclinical models of neurodegenerative diseases, ischemia, and epilepsy to investigate glutamate-related mechanisms. The hydrochloride salt enhances solubility and handling for laboratory use.
| CAS Number | 2450268-84-3 |
| Synonyms | (2S)-2-amino-4-[4-(2-bromo-4,5-difluorophenoxy)anilino]-4-oxobutanoic acid;hydrochloride |
| Molecular Formula | C16H14BrClF2N2O4 |
| Purity | ≥95% |
| IUPAC Name | (2S)-2-amino-4-[4-(2-bromo-4,5-difluorophenoxy)anilino]-4-oxobutanoic acid;hydrochloride |
| InChI | InChI=1S/C16H13BrF2N2O4.ClH/c17-10-5-11(18)12(19)6-14(10)25-9-3-1-8(2-4-9)21-15(22)7-13(20)16(23)24;/h1-6,13H,7,20H2,(H,21,22)(H,23,24);1H/t13-;/m0./s1 |
| InChIKey | IBCWXGJQAQXHPZ-ZOWNYOTGSA-N |
| SMILES | C1=CC(=CC=C1NC(=O)C[C@@H](C(=O)O)N)OC2=CC(=C(C=C2Br)F)F.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
