For research use only. Not for therapeutic Use.
VU0422288（Cat No.:I011180）is a highly selective antagonist of the M5 muscarinic acetylcholine receptor (M5 mAChR), a G protein-coupled receptor implicated in dopaminergic signaling and central nervous system (CNS) function. By selectively blocking M5 receptors, VU0422288 enables researchers to study the role of M5 in modulating dopamine release, drug addiction, and neuropsychiatric disorders such as schizophrenia. It exhibits minimal activity at other muscarinic receptor subtypes, ensuring specificity in pharmacological studies. VU0422288 is a valuable tool for dissecting cholinergic mechanisms and exploring novel therapeutic targets within the CNS for cognitive and behavioral disorders.
| CAS Number | 1630936-95-6 |
| Synonyms | N-[3-chloro-4-(5-chloropyridin-2-yl)oxyphenyl]pyridine-2-carboxamide |
| Molecular Formula | C17H11Cl2N3O2 |
| Purity | ≥95% |
| IUPAC Name | N-[3-chloro-4-(5-chloropyridin-2-yl)oxyphenyl]pyridine-2-carboxamide |
| InChI | InChI=1S/C17H11Cl2N3O2/c18-11-4-7-16(21-10-11)24-15-6-5-12(9-13(15)19)22-17(23)14-3-1-2-8-20-14/h1-10H,(H,22,23) |
| InChIKey | MZRLPXFGQKQHST-UHFFFAOYSA-N |
| SMILES | C1=CC=NC(=C1)C(=O)NC2=CC(=C(C=C2)OC3=NC=C(C=C3)Cl)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
