VU0360172

For research use only. Not for therapeutic Use.

  • CAT Number: I038144
  • CAS Number: 1310012-12-4
  • Molecular Formula: C18H15FN2O
  • Molecular Weight: 294.32
  • Purity: ≥95%
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VU0360172(Cat No.:I038144)is a potent and selective small-molecule inhibitor of the GPR35 receptor, a G protein-coupled receptor involved in regulating various physiological processes, including inflammation and immune responses. By modulating GPR35 activity, VU0360172 has shown potential in preclinical studies to reduce inflammation and impact conditions like inflammatory bowel disease (IBD) and asthma. Its selective inhibition of GPR35 offers a targeted approach to treating disorders linked to immune dysregulation and chronic inflammation. Ongoing research is focused on evaluating its therapeutic efficacy and safety profile for clinical applications in inflammatory diseases.


CAS Number 1310012-12-4
Synonyms

N-cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]pyridine-3-carboxamide

Molecular Formula C18H15FN2O
Purity ≥95%
IUPAC Name N-cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]pyridine-3-carboxamide
InChI InChI=1S/C18H15FN2O/c19-15-4-1-3-13(11-15)7-9-16-10-8-14(12-20-16)18(22)21-17-5-2-6-17/h1,3-4,8,10-12,17H,2,5-6H2,(H,21,22)
InChIKey NEMHWVUKNWAKTM-UHFFFAOYSA-N
SMILES C1CC(C1)NC(=O)C2=CN=C(C=C2)C#CC3=CC(=CC=C3)F
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