For research use only. Not for therapeutic Use.
Vipoglanstat（Cat No.:I043358）is an investigational small-molecule inhibitor targeting the enzyme Janus kinase 1 (JAK1), a key player in the signaling pathways of various cytokines involved in immune response and inflammation. By selectively inhibiting JAK1, Vipoglanstat aims to modulate the immune system, offering therapeutic potential for autoimmune diseases, chronic inflammatory conditions, and certain types of cancer. This compound has shown promise in preclinical studies, particularly in reducing inflammation and improving symptoms in diseases like rheumatoid arthritis and psoriasis. Research continues to explore its efficacy, safety, and long-term therapeutic potential in clinical settings.
| CAS Number | 1360622-01-0 |
| Synonyms | 2-[2,6-dichloro-3-[(2,2-dimethylpropanoylamino)methyl]anilino]-6-(2,2-difluoroethoxy)-1-methyl-N-[4-(trifluoromethyl)cyclohexyl]benzimidazole-5-carboxamide |
| Molecular Formula | C30H34Cl2F5N5O3 |
| Purity | ≥95% |
| IUPAC Name | 2-[2,6-dichloro-3-[(2,2-dimethylpropanoylamino)methyl]anilino]-6-(2,2-difluoroethoxy)-1-methyl-N-[4-(trifluoromethyl)cyclohexyl]benzimidazole-5-carboxamide |
| InChI | InChI=1S/C30H34Cl2F5N5O3/c1-29(2,3)27(44)38-13-15-5-10-19(31)25(24(15)32)41-28-40-20-11-18(22(45-14-23(33)34)12-21(20)42(28)4)26(43)39-17-8-6-16(7-9-17)30(35,36)37/h5,10-12,16-17,23H,6-9,13-14H2,1-4H3,(H,38,44)(H,39,43)(H,40,41) |
| InChIKey | PFORUFFGGNOLPJ-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C(=O)NCC1=C(C(=C(C=C1)Cl)NC2=NC3=C(N2C)C=C(C(=C3)C(=O)NC4CCC(CC4)C(F)(F)F)OCC(F)F)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
