Vindoline

For research use only. Not for therapeutic Use.

  • CAT Number: R008728
  • CAS Number: 2182-14-1
  • Molecular Formula: C25H32N2O6
  • Molecular Weight: 456.53
  • Purity: ≥95%
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Vindoline(CAT:R008728) is a monoterpenoid indole alkaloid isolated from Catharanthus roseus (Madagascar periwinkle), a plant well known for its rich repertoire of bioactive alkaloids. While Vindoline itself shows moderate anticancer, anti-inflammatory, and antioxidant properties, its greatest importance lies in being a biosynthetic precursor of clinically significant anticancer drugs such as vinblastine and vincristine. Research highlights its role in modulating cell proliferation, oxidative stress, and inflammatory signaling, making it valuable in cancer and metabolic disease studies. With its unique indole alkaloid structure and pharmaceutical relevance, Vindoline is a key natural compound in drug discovery, biosynthetic pathway studies, and medicinal chemistry.


CAS Number 2182-14-1
Synonyms

methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate

Molecular Formula C25H32N2O6
Purity ≥95%
IUPAC Name methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2(7),3,5,13-tetraene-10-carboxylate
InChI InChI=1S/C25H32N2O6/c1-6-23-10-7-12-27-13-11-24(19(23)27)17-9-8-16(31-4)14-18(17)26(3)20(24)25(30,22(29)32-5)21(23)33-15(2)28/h7-10,14,19-21,30H,6,11-13H2,1-5H3/t19-,20+,21+,23+,24+,25-/m0/s1
InChIKey CXBGOBGJHGGWIE-ACSXSLCXSA-N
SMILES CCC12C=CCN3C1C4(CC3)C(C(C2OC(=O)C)(C(=O)OC)O)N(C5=C4C=CC(=C5)OC)C
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