Vinaxanthone

• CAT Number: I038051
• CAS Number: 133293-89-7
• Molecular Formula: C28H16O14
• Molecular Weight: 576.42
• Purity: ≥95%
• Synonyms: 5,7-diacetyl-6-(5-carboxy-6,7-dihydroxy-4-oxochromen-3-yl)-2,3-dihydroxy-9-oxoxanthene-1-carboxylic acid
• InChI: InChI=1S/C28H16O14/c1-7(29)9-3-10-22(33)19-15(5-13(32)25(36)21(19)28(39)40)42-26(10)16(8(2)30)17(9)11-6-41-14-4-12(31)24(35)20(27(37)38)18(14)23(11)34/h3-6,31-32,35-36H,1-2H3,(H,37,38)(H,39,40)
• InChIKey: MEYYEMQDVMMNNR-UHFFFAOYSA-N
• SMILES: CC(=O)C1=C(C(=C2C(=C1)C(=O)C3=C(O2)C=C(C(=C3C(=O)O)O)O)C(=O)C)C4=COC5=C(C4=O)C(=C(C(=C5)O)O)C(=O)O

Vinaxanthone（Cat No.:I038051）is a synthetic small molecule known for its neuroprotective and anti-inflammatory properties, primarily through inhibition of semaphorin 3A (Sema3A) signaling. Sema3A is involved in neuronal guidance and immune responses, and its dysregulation is linked to neurodegenerative diseases and nerve injury. By blocking Sema3A, vinaxanthone promotes axonal regeneration, enhances neuronal survival, and reduces inflammation. It is widely studied in models of multiple sclerosis, spinal cord injury, and neuropathic pain. Vinaxanthone holds promise as a therapeutic candidate for promoting neural repair and modulating immune responses in neuroinflammatory disorders.