For research use only. Not for therapeutic Use.
Vimnerixin (Cat No.:I045080) is an investigational oral stimulator of the Stimulator of Interferon Genes (STING) pathway, designed to enhance innate immune responses against cancer. By activating STING, vimnerixin promotes the production of type I interferons and proinflammatory cytokines, leading to increased dendritic cell activation and T-cell priming. This immune stimulation enhances antitumor activity, especially when used in combination with immune checkpoint inhibitors. Vimnerixin offers a non-injectable approach to STING activation, making it a promising candidate for cancer immunotherapy with potential applications in solid tumors and immune-refractory cancers.
| CAS Number | 1418112-77-2 |
| Synonyms | N-[6-[(2R,3S)-3,4-dihydroxybutan-2-yl]oxy-2-[(4-fluorophenyl)methylsulfanyl]pyrimidin-4-yl]-3-methylazetidine-1-sulfonamide |
| Molecular Formula | C19H25FN4O5S2 |
| Purity | ≥95% |
| IUPAC Name | N-[6-[(2R,3S)-3,4-dihydroxybutan-2-yl]oxy-2-[(4-fluorophenyl)methylsulfanyl]pyrimidin-4-yl]-3-methylazetidine-1-sulfonamide |
| InChI | InChI=1S/C19H25FN4O5S2/c1-12-8-24(9-12)31(27,28)23-17-7-18(29-13(2)16(26)10-25)22-19(21-17)30-11-14-3-5-15(20)6-4-14/h3-7,12-13,16,25-26H,8-11H2,1-2H3,(H,21,22,23)/t13-,16+/m1/s1 |
| InChIKey | UCCNQCNIPRKLRP-CJNGLKHVSA-N |
| SMILES | CC1CN(C1)S(=O)(=O)NC2=CC(=NC(=N2)SCC3=CC=C(C=C3)F)O[C@H](C)[C@H](CO)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
