For research use only. Not for therapeutic Use.
viFSP1(CAT: I040511) is a species-independent, direct inhibitor of ferroptosis suppressor protein 1 (FSP1), a key regulator of cellular lipid peroxidation resistance. By targeting the conserved NAD(P)H binding pocket of FSP1, viFSP1 disrupts its antioxidative function, thereby promoting lipid peroxidation and inducing ferroptotic cell death in FSP1-dependent cells. This compound exhibits strong anticancer potential, particularly in tumors relying on FSP1 for survival under oxidative stress. viFSP1 is an invaluable tool for investigating ferroptosis mechanisms, redox biology, and therapeutic strategies against resistant cancer types. Supplied in high purity, it is suitable for biochemical assays, mechanistic studies, and oncology-focused drug discovery.
| CAS Number | 951945-67-8 |
| Synonyms | 1-(2,4-dimethoxyphenyl)-5-imino-4-(4-methyl-1,3-thiazol-2-yl)-2H-pyrrol-3-ol |
| Molecular Formula | C16H17N3O3S |
| Purity | ≥95% |
| IUPAC Name | 1-(2,4-dimethoxyphenyl)-5-imino-4-(4-methyl-1,3-thiazol-2-yl)-2H-pyrrol-3-ol |
| InChI | InChI=1S/C16H17N3O3S/c1-9-8-23-16(18-9)14-12(20)7-19(15(14)17)11-5-4-10(21-2)6-13(11)22-3/h4-6,8,17,20H,7H2,1-3H3 |
| InChIKey | WIFWMPYWKNDQSJ-UHFFFAOYSA-N |
| SMILES | CC1=CSC(=N1)C2=C(CN(C2=N)C3=C(C=C(C=C3)OC)OC)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
