Verucopeptin

For research use only. Not for therapeutic Use.

  • CAT Number: M105942
  • CAS Number: 138067-14-8
  • Molecular Formula: C43H73N7O13
  • Molecular Weight: 896.08
  • Purity: ≥95%
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Verucopeptin(Cat No.:M105942)is a synthetic peptide antibiotic known for its ability to inhibit bacterial protein synthesis by targeting the ribosome. It belongs to a class of ribosomally synthesized and post-translationally modified peptides (RiPPs) and exhibits potent antimicrobial activity, particularly against Gram-positive pathogens. Verucopeptin interferes with the translational machinery, disrupting peptide bond formation and halting bacterial growth. It is under investigation for its potential in addressing antibiotic resistance. Its unique mechanism and structural features make it a valuable tool in antimicrobial research and a promising lead for novel antibiotic development.


CAS Number 138067-14-8
Synonyms

(2S)-2-hydroxy-N-[(3S,4S,19R)-17-hydroxy-8,14-dimethyl-2,6,9,12,15,18-hexaoxo-4-propan-2-yl-5-oxa-1,8,11,14,17,23-hexazabicyclo[17.4.0]tricosan-3-yl]-2-[(5S,6R)-2-hydroxy-5-methoxy-6-[(E,4S,6S,8R)-4,6,8-trimethyldec-2-en-2-yl]oxan-2-yl]propanamide

Molecular Formula C43H73N7O13
Purity ≥95%
IUPAC Name 2-hydroxy-N-(17-hydroxy-8,14-dimethyl-2,6,9,12,15,18-hexaoxo-4-propan-2-yl-5-oxa-1,8,11,14,17,23-hexazabicyclo[17.4.0]tricosan-3-yl)-2-[2-hydroxy-5-methoxy-6-[(E)-4,6,8-trimethyldec-2-en-2-yl]oxan-2-yl]propanamide
InChI InChI=1S/C43H73N7O13/c1-12-26(4)18-27(5)19-28(6)20-29(7)38-31(61-11)15-16-43(59,63-38)42(8,58)41(57)46-36-37(25(2)3)62-35(54)24-48(10)33(52)21-44-32(51)22-47(9)34(53)23-49(60)39(55)30-14-13-17-45-50(30)40(36)56/h20,25-28,30-31,36-38,45,58-60H,12-19,21-24H2,1-11H3,(H,44,51)(H,46,57)/b29-20+
InChIKey IKTLLLGZSOKVRF-ZTKZIYFRSA-N
SMILES CCC(C)CC(C)CC(C)/C=C(\C)/C1C(CCC(O1)(C(C)(C(=O)NC2C(OC(=O)CN(C(=O)CNC(=O)CN(C(=O)CN(C(=O)C3CCCNN3C2=O)O)C)C)C(C)C)O)O)OC
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