Vecuronium Bromide

• CAT Number: A000682
• CAS Number: 50700-72-6
• Molecular Formula: C34H57BrN2O4
• Molecular Weight: 637.71
• Purity: ≥95%
• Synonyms: 50700-72-6; Norcuron; ORG NC 45; Vecuronii bromidum; Bromuro de vecuronio
• Target: Neuronal Signaling
• Solubility: >23.5mg/mL in DMSO
• Storage: -20°C
• IUPAC Name: [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetyloxy-10,13-dimethyl-16-(1-methylpiperidin-1-ium-1-yl)-2-piperidin-1-yl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate;bromide
• InChI: 1S/C34H57N2O4.BrH/c1-23(37)39-31-20-25-12-13-26-27(34(25,4)22-29(31)35-16-8-6-9-17-35)14-15-33(3)28(26)21-30(32(33)40-24(2)38)36(5)18-10-7-11-19-36;/h25-32H,6-22H2,1-5H3;1H/q+1;/p-1/t25-,26+,27-,28-,29-,30-,31-,32-,33-,34-;/m0./s1
• InChIKey: VEPSYABRBFXYIB-PWXDFCLTSA-M
• SMILES: CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@@H]([C@]2(C[C@@H]1N4CCCCC4)C)CC[C@]5([C@H]3C[C@@H]([C@@H]5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-]

Vecuronium bromide(CAT: A000682) is a non-depolarizing neuromuscular blocking agent with the molecular formula C₃₄H₅₇BrN₂O₄, belonging to the aminosteroid class of muscle relaxants. It appears as a white to off-white crystalline powder, freely soluble in water. Vecuronium bromide works by competitively blocking nicotinic acetylcholine receptors at the neuromuscular junction, inhibiting nerve impulse transmission and causing reversible skeletal muscle relaxation. Clinically, it is used as an adjunct to general anesthesia to facilitate tracheal intubation and provide muscle relaxation during surgery or mechanical ventilation. Its intermediate duration of action, minimal cardiovascular effects, and predictable recovery profile make it a widely used agent in anesthesia practice.