For research use only. Not for therapeutic Use.
Valsartan Ethyl Ester(CAT: R026253) is a synthetic derivative and prodrug form of Valsartan, a widely used angiotensin II type 1 receptor (AT1R) antagonist for the management of hypertension, heart failure, and related cardiovascular conditions. The ethyl ester modification enhances lipophilicity and may improve membrane permeability, making it a useful intermediate in drug metabolism, pharmacokinetic, and prodrug studies. As a reference compound, Valsartan Ethyl Ester aids in exploring the absorption, distribution, and bioactivation of angiotensin receptor blockers. It is a valuable tool for cardiovascular disease research, supporting studies in RAAS signaling, hypertension therapy, and medicinal chemistry development.
| CAS Number | 1111177-30-0 |
| Synonyms | ethyl (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate |
| Molecular Formula | C26H33N5O3 |
| Purity | ≥95% |
| IUPAC Name | ethyl (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate |
| InChI | InChI=1S/C26H33N5O3/c1-5-7-12-23(32)31(24(18(3)4)26(33)34-6-2)17-19-13-15-20(16-14-19)21-10-8-9-11-22(21)25-27-29-30-28-25/h8-11,13-16,18,24H,5-7,12,17H2,1-4H3,(H,27,28,29,30)/t24-/m0/s1 |
| InChIKey | BTSNVLAJCYDJEU-DEOSSOPVSA-N |
| SMILES | CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)OCC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
