For research use only. Not for therapeutic Use.
Valiltramiprosate (Cat No.:I018164) is an orally bioavailable prodrug of tramiprosate, designed to improve brain penetration and gastrointestinal tolerability. It acts by binding to amyloid-β (Aβ) peptides, preventing their aggregation into toxic oligomers and fibrils, which are implicated in Alzheimer’s disease pathology. Clinical studies indicate Valiltramiprosate may slow cognitive decline and preserve function in patients with APOE4-associated Alzheimer’s disease. With enhanced pharmacokinetic properties, it represents a promising candidate for disease-modifying therapy, and a valuable compound for research into neurodegeneration and amyloid-targeted drug development.
| CAS Number | 1034190-08-3 |
| Synonyms | 3-[[(2S)-2-amino-3-methylbutanoyl]amino]propane-1-sulfonic acid |
| Molecular Formula | C8H18N2O4S |
| Purity | ≥95% |
| IUPAC Name | 3-[[(2S)-2-amino-3-methylbutanoyl]amino]propane-1-sulfonic acid |
| InChI | InChI=1S/C8H18N2O4S/c1-6(2)7(9)8(11)10-4-3-5-15(12,13)14/h6-7H,3-5,9H2,1-2H3,(H,10,11)(H,12,13,14)/t7-/m0/s1 |
| InChIKey | NRZRFNYKMSAZBI-ZETCQYMHSA-N |
| SMILES | CC(C)[C@@H](C(=O)NCCCS(=O)(=O)O)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
