UV Cleavable Biotin-PEG2-Azide

• CAT Number: I045909
• CAS Number: 1192802-98-4
• Molecular Formula: C38H51N7O9S
• Molecular Weight: 781.92
• Purity: ≥95%
• Synonyms: [1-[3-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethylamino]-2-oxoethoxy]phenyl]-2-oxo-2-phenylethyl] 6-azidohexanoate
• InChI: InChI=1S/C38H51N7O9S/c39-45-42-17-8-2-5-16-34(48)54-37(36(49)27-10-3-1-4-11-27)28-12-9-13-29(24-28)53-25-33(47)41-19-21-52-23-22-51-20-18-40-32(46)15-7-6-14-31-35-30(26-55-31)43-38(50)44-35/h1,3-4,9-13,24,30-31,35,37H,2,5-8,14-23,25-26H2,(H,40,46)(H,41,47)(H2,43,44,50)/t30-,31-,35-,37?/m0/s1
• InChIKey: JHYKDGNZEADRIH-ZPIGJYFOSA-N
• SMILES: C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCOCCOCCNC(=O)COC3=CC=CC(=C3)C(C(=O)C4=CC=CC=C4)OC(=O)CCCCCN=[N+]=[N-])NC(=O)N2

UV Cleavable Biotin-PEG2-Azide（Cat No.:I045909）is a specialized heterobifunctional probe combining biotin for strong streptavidin/avidin binding, a PEG2 spacer for hydrophilicity and reduced steric hindrance, and an azide group for click chemistry with alkynes. Its unique UV-cleavable linker allows controlled release of captured biomolecules upon light exposure, enabling reversible labeling and purification. The compact PEG2 chain enhances solubility and flexibility while maintaining reactivity in aqueous and mixed systems. This reagent is widely applied in proteomics, chemical biology, and drug discovery for controlled enrichment and photo-triggered molecular release.