For research use only. Not for therapeutic Use.
USP7-IN-9（Cat No.:I043826）is a selective small molecule inhibitor targeting USP7 (ubiquitin-specific protease 7), a deubiquitinating enzyme that regulates protein stability and various cellular processes, including cell cycle progression, DNA repair, and immune response. USP7 is known to deubiquitinate key regulatory proteins, such as p53 and Mdm2, influencing tumor growth and immune evasion. By inhibiting USP7, USP7-IN-9 disrupts these processes, making it a promising candidate for cancer therapy. Preclinical studies suggest that USP7-IN-9 may enhance anti-tumor immunity and increase the efficacy of existing cancer treatments by modulating protein degradation pathways.
| CAS Number | 2444374-01-8 |
| Synonyms | [4-[6-[[1-[(2-chloro-4-methoxycarbonylphenyl)methyl]-4-hydroxypiperidin-1-ium-4-yl]methyl]-2-methyl-7-oxopyrazolo[4,3-d]pyrimidin-3-yl]phenyl]methylazanium;2,2,2-trifluoroacetate |
| Molecular Formula | C32H33ClF6N6O8 |
| Purity | ≥95% |
| IUPAC Name | [4-[6-[[1-[(2-chloro-4-methoxycarbonylphenyl)methyl]-4-hydroxypiperidin-1-ium-4-yl]methyl]-2-methyl-7-oxopyrazolo[4,3-d]pyrimidin-3-yl]phenyl]methylazanium;2,2,2-trifluoroacetate |
| InChI | InChI=1S/C28H31ClN6O4.2C2HF3O2/c1-33-25(19-5-3-18(14-30)4-6-19)23-24(32-33)26(36)35(17-31-23)16-28(38)9-11-34(12-10-28)15-21-8-7-20(13-22(21)29)27(37)39-2;2*3-2(4,5)1(6)7/h3-8,13,17,38H,9-12,14-16,30H2,1-2H3;2*(H,6,7) |
| InChIKey | WZRJDCAJOKOZRD-UHFFFAOYSA-N |
| SMILES | CN1C(=C2C(=N1)C(=O)N(C=N2)CC3(CC[NH+](CC3)CC4=C(C=C(C=C4)C(=O)OC)Cl)O)C5=CC=C(C=C5)C[NH3+].C(=O)(C(F)(F)F)[O-].C(=O)(C(F)(F)F)[O-] |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
