For research use only. Not for therapeutic Use.
USP7-IN-8（Cat No.:I044540）is a potent and selective small-molecule inhibitor of ubiquitin-specific protease 7 (USP7), a deubiquitinating enzyme that regulates protein stability, including key targets like p53 and MDM2. By inhibiting USP7, USP7-IN-8 promotes the degradation of oncogenic proteins and stabilizes tumor suppressors, leading to apoptosis in cancer cells. It demonstrates strong cellular activity and selectivity, making it a valuable tool for investigating the role of deubiquitination in cancer biology. USP7-IN-8 holds therapeutic potential in oncology, particularly in tumors with dysregulated ubiquitin-proteasome pathways and impaired p53 signaling.
| CAS Number | 2009273-60-1 |
| Synonyms | 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]-N-methylbenzamide |
| Molecular Formula | C21H21N3O2 |
| Purity | ≥95% |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
