For research use only. Not for therapeutic Use.
USP5-IN-1（Cat No.:I044166）is a selective small-molecule inhibitor of ubiquitin-specific protease 5 (USP5), a deubiquitinating enzyme involved in cleaving unanchored polyubiquitin chains and regulating protein degradation. By inhibiting USP5, USP5-IN-1 disrupts proteasome function and alters the stability of various cellular proteins, impacting processes like cell cycle progression, DNA repair, and apoptosis. It is widely used in cancer research to study the role of ubiquitin signaling in tumor growth and survival. USP5-IN-1 also offers therapeutic potential in neurodegenerative and inflammatory diseases where dysregulated protein homeostasis plays a critical role.
| CAS Number | 2851040-81-6 |
| Synonyms | 2-[[5-[4-(4-chlorophenyl)piperidin-1-yl]sulfonylpyridine-2-carbonyl]amino]acetic acid |
| Molecular Formula | C19H20ClN3O5S |
| Purity | ≥95% |
| IUPAC Name | 2-[[5-[4-(4-chlorophenyl)piperidin-1-yl]sulfonylpyridine-2-carbonyl]amino]acetic acid |
| InChI | InChI=1S/C19H20ClN3O5S/c20-15-3-1-13(2-4-15)14-7-9-23(10-8-14)29(27,28)16-5-6-17(21-11-16)19(26)22-12-18(24)25/h1-6,11,14H,7-10,12H2,(H,22,26)(H,24,25) |
| InChIKey | HIWYRXWPCQHOSO-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1C2=CC=C(C=C2)Cl)S(=O)(=O)C3=CN=C(C=C3)C(=O)NCC(=O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
