For research use only. Not for therapeutic Use.
Usmarapride (Cat No.: I045553) is a selective dopamine D2/D3 receptor antagonist investigated for the treatment of schizophrenia and other psychiatric disorders. By modulating dopaminergic neurotransmission, it reduces symptoms associated with psychosis while aiming to minimize side effects commonly linked to conventional antipsychotics. Preclinical and early clinical studies suggest Usmarapride may provide improved efficacy and tolerability profiles. In research, it serves as a valuable pharmacological tool for studying dopamine receptor signaling, antipsychotic drug mechanisms, and the development of novel therapies for neuropsychiatric conditions.
CAS Number | 1428862-33-2 |
Synonyms | 2-[1-(3-methoxypropyl)piperidin-4-yl]-5-(1-propan-2-ylindazol-3-yl)-1,3,4-oxadiazole;oxalic acid |
Molecular Formula | C23H31N5O6 |
Purity | ≥95% |
InChI | InChI=1S/C21H29N5O2.C2H2O4/c1-15(2)26-18-8-5-4-7-17(18)19(24-26)21-23-22-20(28-21)16-9-12-25(13-10-16)11-6-14-27-3;3-1(4)2(5)6/h4-5,7-8,15-16H,6,9-14H2,1-3H3;(H,3,4)(H,5,6) |
InChIKey | XHXCJKNEBFAUSE-UHFFFAOYSA-N |
SMILES | CC(C)N1C2=CC=CC=C2C(=N1)C3=NN=C(O3)C4CCN(CC4)CCCOC.C(=O)(C(=O)O)O |
Reference | [1]. Nirogi, Ramakrishna; Mohammed, Abdul Rasheed; Yarlgadda, Suresh; Ravella, Srinivasa Rao; Shinde, Anil Karbhari; Kambhampati, Ramasastri; Roayalley, Praveen Kumar; Jayarajan, Pradeep; Bhyrapuneni, Gopinadh; Patnala, Sriramachandra Murthy; et al. Preparatio |
Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |