For research use only. Not for therapeutic Use.
Urease‑IN‑6(CAT: I040359) is a potent small‑molecule inhibitor of urease, exhibiting an IC₅₀ of 14.2 μM. This thiourea‑based compound selectively blocks the nickel‑dependent active site of urease, making it a valuable tool in exploring enzymatic mechanisms and pathogenic processes. Urease inhibition by Urease‑IN‑6 is used in preclinical research into digestive conditions—particularly peptic and gastric ulcers—by mitigating excessive ammonia production from urea hydrolysis. Supplied as a solid, this compound supports studies in bacterial infection, agricultural nitrogen management, and urinary tract pathophysiology. With high purity (> 98 %) and stability under standard lab storage, Urease‑IN‑6 is well‑suited for biochemical and pharmacological assays
| CAS Number | 362502-79-2 |
| Synonyms | 1-[2-(1H-indol-3-yl)ethyl]-3-(4-methoxyphenyl)thiourea |
| Molecular Formula | C18H19N3OS |
| Purity | ≥95% |
| IUPAC Name | 1-[2-(1H-indol-3-yl)ethyl]-3-(4-methoxyphenyl)thiourea |
| InChI | InChI=1S/C18H19N3OS/c1-22-15-8-6-14(7-9-15)21-18(23)19-11-10-13-12-20-17-5-3-2-4-16(13)17/h2-9,12,20H,10-11H2,1H3,(H2,19,21,23) |
| InChIKey | USHGHTOQCIQMRQ-UHFFFAOYSA-N |
| SMILES | COC1=CC=C(C=C1)NC(=S)NCCC2=CNC3=CC=CC=C32 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
