UniPR129

• CAT Number: I037855
• CAS Number: 1639159-47-9
• Molecular Formula: C36H52N2O4
• Molecular Weight: 576.81
• Purity: ≥95%
• Synonyms: (3S)-3-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]-4-(1H-indol-3-yl)butanoic acid
• InChI: InChI=1S/C36H52N2O4/c1-22(8-13-33(40)38-25(20-34(41)42)18-23-21-37-32-7-5-4-6-27(23)32)29-11-12-30-28-10-9-24-19-26(39)14-16-35(24,2)31(28)15-17-36(29,30)3/h4-7,21-22,24-26,28-31,37,39H,8-20H2,1-3H3,(H,38,40)(H,41,42)/t22-,24-,25+,26-,28+,29-,30+,31+,35+,36-/m1/s1
• InChIKey: JGYYGEYIQBZUCC-ZOOAIUBFSA-N
• SMILES: C[C@H](CCC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)CC(=O)O)[C@H]3CC[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC[C@H]6[C@@]5(CC[C@H](C6)O)C)C

UniPR129（Cat No.:I037855）is a small-molecule inhibitor that targets the Eph/ephrin signaling pathway, specifically disrupting the interaction between EphA2 receptors and their ephrin-A1 ligands. This pathway plays a crucial role in tumor growth, angiogenesis, and metastasis. UniPR129 has demonstrated anticancer activity by impairing cell migration, invasion, and tumor vascularization. It is used in cancer biology research to investigate the role of Eph receptors in oncogenic processes. Due to its specificity and efficacy, UniPR129 is considered a promising lead compound for developing targeted therapies against EphA2-overexpressing tumors.