For research use only. Not for therapeutic Use.
UMB298（Cat No.:I044444）is a selective small-molecule inhibitor of the lysophosphatidic acid receptor 1 (LPA1), a G protein-coupled receptor involved in diverse biological processes including fibrosis, inflammation, and cancer progression. By antagonizing LPA1, UMB298 blocks lysophosphatidic acid (LPA)-mediated signaling pathways that promote cell proliferation, migration, and survival. It has demonstrated potential in preclinical models for treating pulmonary fibrosis, neuropathic pain, and other LPA-driven pathologies. UMB298 is a valuable tool in studying LPA receptor biology and supports therapeutic development aimed at modulating LPA signaling in fibrotic, inflammatory, and oncologic diseases.
| CAS Number | 2266569-73-5 |
| Synonyms | 2-[2-(3-chloro-4-methoxyphenyl)ethyl]-N-cyclohexyl-7-(3,5-dimethyl-1,2-oxazol-4-yl)imidazo[1,2-a]pyridin-3-amine |
| Molecular Formula | C27H31ClN4O2 |
| Purity | ≥95% |
| IUPAC Name | 2-[2-(3-chloro-4-methoxyphenyl)ethyl]-N-cyclohexyl-7-(3,5-dimethyl-1,2-oxazol-4-yl)imidazo[1,2-a]pyridin-3-amine |
| InChI | InChI=1S/C27H31ClN4O2/c1-17-26(18(2)34-31-17)20-13-14-32-25(16-20)30-23(27(32)29-21-7-5-4-6-8-21)11-9-19-10-12-24(33-3)22(28)15-19/h10,12-16,21,29H,4-9,11H2,1-3H3 |
| InChIKey | NZXSWCLCRDCHGN-UHFFFAOYSA-N |
| SMILES | CC1=C(C(=NO1)C)C2=CC3=NC(=C(N3C=C2)NC4CCCCC4)CCC5=CC(=C(C=C5)OC)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
