UF 010

  • CAT Number: I003966
  • CAS Number: 537672-41-6
  • Molecular Formula: C₁₁H₁₅BrN₂O
  • Molecular Weight: 271.15
  • Purity: ≥95%
Inquiry Now

UF010(CAT: I003966) exhibits strong inhibitory activity against HDACs 3, 2, 1, and 8 with IC50 values ranging from 0.06 μM to 1.5 μM. It demonstrates selectivity for these HDAC isoforms over other HDACs. UF010 acts as a competitive inhibitor with a fast-on/slow-off binding mechanism to HDACs. In vitro studies have shown that UF010 promotes the accumulation of acetylated histones, leading to cell cycle arrest at the G1/S transition and inhibiting the proliferation of various cancer cell lines. It also activates tumor suppression mechanisms while inhibiting oncogenic pathways.

Catalog Number I003966
CAS Number 537672-41-6
Molecular Formula


Purity 95%
Target HDAC
Solubility 10 mM in DMSO
Storage -20°C
IC50 0.06 μM (HDAC3), 0.1 μM (HDAC2), 0.5 μM (HDAC1), 1.5 μM(HDAC 8)
InChI 1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15)

<p style=/line-height:25px/>
<br>[1]. Wang Y, et al. Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class I histone deacetylases. Chem Biol. 2015 Feb 19;22(2):273-284.


Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!