UCPH 101(CAT: I010767) is a selective inhibitor of histone methyltransferase enhancer of zeste homolog 2 (EZH2). EZH2 is a key component of the polycomb repressive complex 2 (PRC2) and is involved in the epigenetic regulation of gene expression. UCPH 101 specifically targets the catalytic SET domain of EZH2, inhibiting its methyltransferase activity. By blocking EZH2-mediated histone methylation, UCPH 101 can potentially modulate gene expression patterns and have therapeutic implications in cancer and other diseases where dysregulation of EZH2 is implicated.
| Catalog Number | I010767 |
| CAS Number | 1118460-77-7 |
| Synonyms | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile |
| Molecular Formula | C27H22N2O3 |
| Purity | 95% |
| Solubility | Soluble to 25 mM in DMSO |
| Storage | Store at +4C |
