For research use only. Not for therapeutic Use.
UCCF-853(CAT: I037772) is a small-molecule CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) modulator designed to enhance or restore the function of defective CFTR proteins, which are implicated in cystic fibrosis (CF). By targeting the underlying ion transport defect in epithelial cells, UCCF-853 contributes to improved chloride channel activity and mucociliary clearance. This compound is a valuable research tool for studying CFTR modulation mechanisms, drug response variability, and combination therapy strategies in CF treatment. UCCF-853 supports the development of next-generation CF therapeutics aimed at improving lung function and quality of life for individuals with cystic fibrosis.
| CAS Number | 625458-06-2 |
| Synonyms | 3-(3-chlorophenyl)-6-(trifluoromethyl)-1H-benzimidazol-2-one |
| Molecular Formula | C14H8ClF3N2O |
| Purity | ≥95% |
| IUPAC Name | 3-(3-chlorophenyl)-6-(trifluoromethyl)-1H-benzimidazol-2-one |
| InChI | InChI=1S/C14H8ClF3N2O/c15-9-2-1-3-10(7-9)20-12-5-4-8(14(16,17)18)6-11(12)19-13(20)21/h1-7H,(H,19,21) |
| InChIKey | NMPJFFWYEIIGFW-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC(=C1)Cl)N2C3=C(C=C(C=C3)C(F)(F)F)NC2=O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
