Tyrphostin AG1433

  • CAT Number: I017427
  • CAS Number: 168835-90-3
  • Molecular Formula: C₁₆H₁₄N₂O₂
  • Molecular Weight: 266.29
  • Purity: ≥95%
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Tyrphostin AG1433(CAT: I017427), also known as SU6656, is a potent inhibitor of the Src family of tyrosine kinases. It selectively targets Src and other Src-related kinases, inhibiting their activity by competing with ATP binding. Tyrphostin AG1433 has been widely used as a research tool to investigate the role of Src kinases in various cellular processes, including cell growth, migration, and signal transduction. It has shown potential therapeutic applications in the treatment of cancer, as Src kinases are often dysregulated in cancer cells and play a critical role in tumor progression and metastasis.

Catalog Number I017427
CAS Number 168835-90-3
Molecular Formula


Purity 95%

[1]. Serban F, et al. Silencing of epidermal growth factor, latrophilin and seven transmembrane domain-containing protein 1 (ELTD1) via siRNA-induced cell death in glioblastoma. J Immunoassay Immunochem. 2017;38(1):21-33.<br>[2]. Strawn LM, et al. Flk-1 as a target for tumor growth inhibition. Cancer Res. 1996 Aug 1;56(15):3540-5.<br>[3]. Kim TS, et al. The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress. Dis Model Mech. 2010 Nov-Dec;3(11-12):752-62.<br>[4]. Kroll J, et al. The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells. J Biol Chem. 1997 Dec 19;272(51):32521-7.

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