Tyrphostin AG1433

  • CAT Number: I017427
  • CAS Number: 168835-90-3
  • Molecular Formula: C₁₆H₁₄N₂O₂
  • Molecular Weight: 266.29
  • Purity: ≥95%
Inquiry Now

Tyrphostin AG1433(CAT: I017427), also known as SU6656, is a potent inhibitor of the Src family of tyrosine kinases. It selectively targets Src and other Src-related kinases, inhibiting their activity by competing with ATP binding. Tyrphostin AG1433 has been widely used as a research tool to investigate the role of Src kinases in various cellular processes, including cell growth, migration, and signal transduction. It has shown potential therapeutic applications in the treatment of cancer, as Src kinases are often dysregulated in cancer cells and play a critical role in tumor progression and metastasis.

Catalog Number I017427
CAS Number 168835-90-3
Molecular Formula

C₁₆H₁₄N₂O₂

Purity 95%
Reference

[1]. Serban F, et al. Silencing of epidermal growth factor, latrophilin and seven transmembrane domain-containing protein 1 (ELTD1) via siRNA-induced cell death in glioblastoma. J Immunoassay Immunochem. 2017;38(1):21-33.<br>[2]. Strawn LM, et al. Flk-1 as a target for tumor growth inhibition. Cancer Res. 1996 Aug 1;56(15):3540-5.<br>[3]. Kim TS, et al. The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress. Dis Model Mech. 2010 Nov-Dec;3(11-12):752-62.<br>[4]. Kroll J, et al. The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells. J Biol Chem. 1997 Dec 19;272(51):32521-7.

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!