Tyrosinase-related Protein 2 (TRP-2) (181-188)

• CAT Number: I044266
• CAS Number: 187671-49-4
• Molecular Formula: C58H73N9O12
• Molecular Weight: 1088.25
• Purity: ≥95%
• IUPAC Name: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylpentanoic acid
• InChI: InChI=1S/C58H73N9O12/c1-32(2)25-47(58(78)79)66-53(73)45(29-38-31-60-41-20-14-13-19-40(38)41)65-57(77)50(34(5)6)67-55(75)44(27-36-17-11-8-12-18-36)62-51(71)42(26-35-15-9-7-10-16-35)61-54(74)46(30-48(69)70)63-52(72)43(64-56(76)49(59)33(3)4)28-37-21-23-39(68)24-22-37/h7-24,31-34,42-47,49-50,60,68H,25-30,59H2,1-6H3,(H,61,74)(H,62,71)(H,63,72)(H,64,76)(H,65,77)(H,66,73)(H,67,75)(H,69,70)(H,78,79)/t42-,43-,44-,45-,46-,47-,49-,50-/m0/s1
• InChIKey: HRXKEXXZGCWJFY-IAWGGNPOSA-N
• SMILES: CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC5=CC=C(C=C5)O)NC(=O)[C@H](C(C)C)N

Tyrosinase-related Protein 2 (TRP-2) (181–188)（Cat No.:I044266）is an 8-amino acid peptide fragment derived from residues 181 to 188 of TRP-2, a melanocyte-specific enzyme involved in melanin biosynthesis. This epitope is recognized by cytotoxic T lymphocytes and is associated with melanoma antigens, making it valuable in cancer immunotherapy and vaccine research. The TRP-2 (181–188) peptide is commonly used in studies of tumor immunology, antigen presentation, and immune response targeting. Its restricted expression in melanoma cells and immunogenicity support its role as a target for T cell-mediated anti-tumor therapies.