Tussilagone

• CAT Number: M002399
• CAS Number: 104012-37-5
• Molecular Formula: C23H34O5
• Molecular Weight: 390.51
• Purity: ≥95%
• Synonyms: [(1S,3aR,5R,7S,7aS)-1-[(1R)-1-acetyloxyethyl]-4-methylidene-2-oxo-7-propan-2-yl-3,3a,5,6,7,7a-hexahydro-1H-inden-5-yl] (E)-3-methylpent-2-enoate
• InChI: InChI=1S/C23H34O5/c1-8-13(4)9-21(26)28-20-11-17(12(2)3)23-18(14(20)5)10-19(25)22(23)15(6)27-16(7)24/h9,12,15,17-18,20,22-23H,5,8,10-11H2,1-4,6-7H3/b13-9+/t15-,17+,18+,20-,22+,23+/m1/s1
• InChIKey: CFUPNMDNSQIWBB-UUVDBSHOSA-N
• SMILES: CCC(=CC(=O)OC1CC(C2C(C1=C)CC(=O)C2C(C)OC(=O)C)C(C)C)C

Tussilagone(CAT: M002399) is a sesquiterpenoid compound isolated from the flower buds of Tussilago farfara (coltsfoot), a traditional medicinal herb used for respiratory ailments. It has been studied for its anti-inflammatory, antioxidant, neuroprotective, and vasorelaxant properties. Research indicates that Tussilagone can inhibit pro-inflammatory cytokines, suppress NF-κB signaling, and protect neurons from oxidative damage, making it relevant for studies in neurodegenerative diseases and inflammation-related disorders. Additionally, it has shown potential in improving vascular function and reducing platelet aggregation, supporting cardiovascular research. With its diverse pharmacological profile, Tussilagone represents a promising natural product for therapeutic exploration in respiratory, neurological, and cardiovascular health.