Tuberculosis inhibitor 12

• CAT Number: I040461
• CAS Number: 793729-44-9
• Molecular Formula: C15H9FN4O3S
• Molecular Weight: 344.32
• Purity: ≥95%
• Synonyms: 2-(4-fluorophenyl)-5-[[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]-1,3,4-oxadiazole
• InChI: InChI=1S/C15H9FN4O3S/c16-10-5-3-9(4-6-10)13-18-17-12(22-13)8-24-15-20-19-14(23-15)11-2-1-7-21-11/h1-7H,8H2
• InChIKey: RDVSQKOJZWNWAZ-UHFFFAOYSA-N
• SMILES: C1=COC(=C1)C2=NN=C(O2)SCC3=NN=C(O3)C4=CC=C(C=C4)F

Tuberculosis inhibitor 12 (compound 12) is an oxadiazole derivative and an inhibitor of Mycobacterium tuberculosis. The inhibition rates of Tuberculosis inhibitor 12 (20 μM) on 7H9-Tw-OADC and 7H9-Tw-OADC reached 82% and 78% respectively[1].

Reference

[1]. Early JV, et al. Oxadiazoles Have Butyrate-Specific Conditional Activity against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2016 May 23;60(6):3608-16.
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