Tris(3-hydroxypropyltriazolylmethyl)amine

• CAT Number: L010034
• CAS Number: 760952-88-3
• Molecular Formula: C18H30N10O3
• Molecular Weight: 434.51
• Purity: ≥95%
• IUPAC Name: 3-[4-[[bis[[1-(3-hydroxypropyl)triazol-4-yl]methyl]amino]methyl]triazol-1-yl]propan-1-ol
• InChI: InChI=1S/C18H30N10O3/c29-7-1-4-26-13-16(19-22-26)10-25(11-17-14-27(23-20-17)5-2-8-30)12-18-15-28(24-21-18)6-3-9-31/h13-15,29-31H,1-12H2
• InChIKey: VAKXPQHQQNOUEZ-UHFFFAOYSA-N
• SMILES: C1=C(N=NN1CCCO)CN(CC2=CN(N=N2)CCCO)CC3=CN(N=N3)CCCO

Tris(3-hydroxypropyltriazolylmethyl)amine(CAT: L010034) is a multidentate ligand composed of a central tertiary amine core substituted with three 1,2,3-triazole arms, each bearing a 3-hydroxypropyl group. This compound is widely used in coordination chemistry, supramolecular assembly, and as a chelating agent in metal complex formation. It is particularly valuable in copper-catalyzed azide–alkyne cycloaddition (CuAAC) reactions, where it acts as a stabilizing ligand for Cu(I) species, enhancing reaction efficiency and selectivity. The hydroxyl groups offer additional hydrogen bonding capabilities and water solubility, making it useful in bioconjugation, click chemistry, and the development of functional materials, sensors, and bioorthogonal labeling tools in chemical biology.