Tris-(benzyltriazolylmethyl)amine

• CAT Number: R032997
• CAS Number: 510758-28-8
• Molecular Formula: C30H30N10
• Molecular Weight: 530.64
• Purity: ≥95%
• Synonyms: 1-(1-Benzyltriazol-4-yl)-N,N-bis[(1-benzyltriazol-4-yl)methyl]methanamine; N,N,N-Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine; TBTA; Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine
• Storage: -20°C
• IUPAC Name: 1-(1-benzyltriazol-4-yl)-N,N-bis[(1-benzyltriazol-4-yl)methyl]methanamine
• InChI: InChI=1S/C30H30N10/c1-4-10-25(11-5-1)16-38-22-28(31-34-38)19-37(20-29-23-39(35-32-29)17-26-12-6-2-7-13-26)21-30-24-40(36-33-30)18-27-14-8-3-9-15-27/h1-15,22-24H,16-21H2
• InChIKey: WKGZJBVXZWCZQC-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)CN2C=C(N=N2)CN(CC3=CN(N=N3)CC4=CC=CC=C4)CC5=CN(N=N5)CC6=CC=CC=C6

Tris-(benzyltriazolylmethyl)amine (Cat No.: R032997) is a multidentate ligand commonly used in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, a cornerstone of “click chemistry.” Featuring three benzyltriazole arms attached to a central amine, TBTA stabilizes Cu(I) ions, enhancing catalytic efficiency and selectivity. It improves reaction rates and minimizes side reactions in bioconjugation and polymer modification. Due to its strong chelating ability and solubility in organic solvents, TBTA is widely employed in chemical biology and synthetic chemistry. For laboratory research use only.