Triphenylphosphine Oxide

• CAT Number: R021654
• CAS Number: 791-28-6
• Molecular Formula: C18H15OP
• Molecular Weight: 278.29
• Purity: ≥95%
• Synonyms: NSC 398; PP 560; TPPO; Triphenyl Phosphorus Oxide; Triphenylphosphine Monoxide; Orlistat Related Compound C
• Storage: -20°C
• IUPAC Name: diphenylphosphorylbenzene
• InChI: InChI=1S/C18H15OP/c19-20(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H
• InChIKey: FIQMHBFVRAXMOP-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3

Triphenylphosphine oxide (Cat No.:R021654) is an organophosphorus compound with the molecular formula C18H15OP. It features a central phosphorus atom double-bonded to oxygen and bonded to three phenyl groups. TPPO is a white crystalline solid, commonly formed as a byproduct in reactions involving triphenylphosphine, such as Wittig or Mitsunobu reactions. It is thermally stable, poorly soluble in water, and soluble in organic solvents like chloroform and dichloromethane. TPPO is also used as a ligand in coordination chemistry and as a polar additive in catalytic and crystallization processes. Proper lab safety protocols are recommended when handling.