Trimethylsilyl Azide

• CAT Number: R044152
• CAS Number: 4648-54-8
• Molecular Formula: C3H9N3Si
• Molecular Weight: 115.21
• Purity: ≥95%
• Synonyms: Azidotrimethylsilane; Trimethylazidosilane; Trimethylsilicon Azide
• Storage: -20°C
• IUPAC Name: azido(trimethyl)silane
• InChI: InChI=1S/C3H9N3Si/c1-7(2,3)6-5-4/h1-3H3
• InChIKey: SEDZOYHHAIAQIW-UHFFFAOYSA-N
• SMILES: C[Si](C)(C)N=[N+]=[N-]

Trimethylsilyl azide (Cat No.:R044152) is an organosilicon compound with the molecular formula C3H9N3Si. It is a colorless to pale yellow, volatile liquid commonly used as a reagent in organic synthesis, particularly for introducing azide groups or facilitating the formation of tetrazoles and other nitrogen-containing heterocycles. TMSN₃ serves as a safer alternative to hydrazoic acid, offering better stability and handling. It reacts readily with electrophiles and is valuable in click chemistry and pharmaceutical intermediate synthesis. Due to its potential explosiveness and toxicity, it must be handled with strict safety precautions.