Trimethylamine N-oxide (Cat No.:M047578) is an organic compound derived from the hepatic oxidation of trimethylamine (TMA), a metabolite produced by gut microbiota from dietary choline, L-carnitine, and betaine. TMAO is naturally present in marine organisms, where it stabilizes proteins against pressure-induced denaturation. In human health, elevated TMAO levels have been linked to cardiovascular diseases, atherosclerosis, and metabolic disorders through effects on cholesterol metabolism and platelet function. It is widely studied in microbiome, cardiovascular, and metabolic research, serving as both a biomarker and therapeutic target in disease pathophysiology.