Triethyl Orthoacetate

• CAT Number: R021038
• CAS Number: 78-39-7
• Molecular Formula: C8H18O3
• Molecular Weight: 162.23
• Purity: ≥95%
• Synonyms: 1,1,1-Triethoxyethane; Orthoacetic Acid Triethyl Ester; Ethyl Orthoacetate; NSC 5596
• Storage: Store at -20°C
• IUPAC Name: 1,1,1-triethoxyethane
• InChI: InChI=1S/C8H18O3/c1-5-9-8(4,10-6-2)11-7-3/h5-7H2,1-4H3
• InChIKey: NDQXKKFRNOPRDW-UHFFFAOYSA-N
• SMILES: CCOC(C)(OCC)OCC

Triethyl orthoacetate (Cat No.:R021038) is an important intermediate for the synthesis of ethyl permethric acid, and is also used in the preparation of alkenes such as trans-tri-substituted alkenes and chiral propadiene, and as a raw material for the dye and pharmaceutical industries.It serves as an ethylating agent and a reagent in the Johnson–Claisen rearrangement to form γ,δ-unsaturated esters. Triethyl orthoacetate is valued for its ability to introduce ethoxy groups and stabilize reactive intermediates, making it useful in pharmaceutical and fine chemical manufacturing.