Transplatin

• CAT Number: R058781
• CAS Number: 14913-33-8
• Molecular Formula: Pt(NH3)2Cl2
• Molecular Weight: 300.05
• Purity: ≥95%
• Synonyms: trans-DDP; trans-Diaminedichloroplatinum; trans-Diamminedichloroplatinum; trans-Diamminedichloroplatinum(II); trans-Dichlorodiamineplatinum(II); trans-Dichlorodiammine Platinum; trans-Dichlorodiammineplatinum(II); trans-Platinum(II) Ammonium Chloride
• Storage: Store at +4C
• IUPAC Name: azane;dichloroplatinum
• InChI: InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
• InChIKey: LXZZYRPGZAFOLE-UHFFFAOYSA-L
• SMILES: N.N.Cl[Pt]Cl

Transplatin（Cat No.:R058781）, or trans-diamminedichloroplatinum(II), is a platinum-based coordination compound with the formula [PtCl₂(NH₃)₂], where the two chloride and two ammine ligands are arranged in a trans configuration. It is the geometric isomer of cisplatin, a well-known anticancer drug. Unlike cisplatin, transplatin exhibits significantly lower anticancer activity due to its different interaction with DNA; it forms linear rather than kinked DNA adducts, which are more easily repaired by cellular mechanisms. Transplatin is primarily used in research to study structure-activity relationships and the biological chemistry of platinum coordination complexes.