trans-4-Hydroxy-D-proline

• CAT Number: R073072
• CAS Number: 3398-22-9
• PubChem Substance ID: 440074
• Molecular Formula: C5H9NO3
• Molecular Weight: 131.13
• Purity: ≥95%
• IUPAC Name: (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid
• InChI: InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m0/s1
• InChIKey: PMMYEEVYMWASQN-IUYQGCFVSA-N
• SMILES: C1[C@@H](CN[C@H]1C(=O)O)O

trans-4-Hydroxy-D-proline（Cat No.:R073072）is a stereoisomer of hydroxyproline, a hydroxylated derivative of the amino acid proline. It features a hydroxyl group at the 4-position in the trans configuration and possesses D-chirality, distinguishing it from the more common L-form found in collagen. This compound is used in biochemical research, particularly in the study of protein structure, peptide synthesis, and enzyme-substrate interactions. It also serves as a building block in the synthesis of peptidomimetics and conformationally constrained peptides. Its unique stereochemistry makes it valuable for probing stereospecific biological processes and structural modifications.