trans-1,2-Cyclohexanediaminetetraacetic acid

• CAT Number: M055074
• CAS Number: 13291-61-7
• Molecular Formula: C14H22N2O8
• Molecular Weight: 346.33
• Purity: ≥95%
• Synonyms: 2-[[(1R,2R)-2-[bis(carboxymethyl)amino]cyclohexyl]-(carboxymethyl)amino]acetic acid
• Related CAS: 125572-95-4 139-13-9 470462-56-7 60-00-4
• InChI: InChI=1S/C14H22N2O8/c17-11(18)5-15(6-12(19)20)9-3-1-2-4-10(9)16(7-13(21)22)8-14(23)24/h9-10H,1-8H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)/t9-,10-/m1/s1
• InChIKey: FCKYPQBAHLOOJQ-NXEZZACHSA-N
• SMILES: C1CC[C@H]([C@@H](C1)N(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O

trans-1,2-Cyclohexanediaminetetraacetic acid (CAT: M055074) is a polyaminocarboxylic acid chelating agent structurally related to EDTA but with a rigid cyclohexane backbone. This configuration enhances its selectivity and complexation strength, particularly with metal ions such as Ca²⁺, Mg²⁺, Fe³⁺, and lanthanides. CDTA is widely used in analytical chemistry, biochemical assays, and industrial water treatment as a powerful sequestering agent. It also finds applications in radiometal labeling, coordination chemistry, and the stabilization of metal-catalyzed processes. The trans-orientation of its diamine groups provides a defined spatial geometry, improving binding affinity and stability of its metal complexes across a broad pH range.