TRAM-39

• CAT Number: I011059
• CAS Number: 197525-99-8
• Molecular Formula: C20H14ClN
• Molecular Weight: 303.78
• Purity: ≥95%
• Synonyms: 2-(2-chlorophenyl)-2,2-diphenylacetonitrile
• InChI: InChI=1S/C20H14ClN/c21-19-14-8-7-13-18(19)20(15-22,16-9-3-1-4-10-16)17-11-5-2-6-12-17/h1-14H
• InChIKey: JHNRTPKGSCVKKC-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C(C#N)(C2=CC=CC=C2)C3=CC=CC=C3Cl

TRAM-39（Cat No.:I011059）is a selective small molecule inhibitor that targets the TRPM2 (Transient Receptor Potential Melastatin 2) ion channel, which plays a key role in regulating cellular responses to oxidative stress and inflammation. By inhibiting TRPM2, TRAM-39 helps modulate calcium influx, which is implicated in various pathophysiological conditions such as neurodegenerative diseases, cardiovascular disorders, and chronic inflammation. This compound is being studied for its potential therapeutic applications in diseases where TRPM2 overactivation contributes to tissue damage and dysfunction, offering a promising approach for managing oxidative stress-related conditions.