TPh A

• CAT Number: I015037
• CAS Number: 21306-65-0
• Molecular Formula: C21H21NO3S2
• Molecular Weight: 399.53
• Purity: ≥95%
• Synonyms: (NE)-4-methyl-N-[methyl-(4-phenylmethoxyphenyl)-λ4-sulfanylidene]benzenesulfonamide
• IUPAC Name: (NE)-4-methyl-N-[methyl-(4-phenylmethoxyphenyl)-lambda4-sulfanylidene]benzenesulfonamide
• InChI: InChI=1S/C21H21NO3S2/c1-17-8-14-21(15-9-17)27(23,24)22-26(2)20-12-10-19(11-13-20)25-16-18-6-4-3-5-7-18/h3-15H,16H2,1-2H3
• InChIKey: IMUPOWQOXOCVBN-UHFFFAOYSA-N
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)/N=S(\C)/C2=CC=C(C=C2)OCC3=CC=CC=C3

TPh A (Cat No.:I015037) is a small-molecule inhibitor known to selectively block mitochondrial permeability transition pore (mPTP) opening, thereby regulating mitochondrial integrity and cell survival. By preventing pore activation, TPh A protects against mitochondrial dysfunction, oxidative stress, and apoptosis. It is widely used in studies of ischemia-reperfusion injury, neurodegeneration, and metabolic disorders, where mitochondrial damage plays a central role. TPh A provides researchers with a valuable tool to explore mitochondrial signaling pathways and to develop therapeutic strategies targeting mitochondrial-related diseases and cellular stress responses.