For research use only. Not for therapeutic Use.
Tos-PEG6-CH2-Boc(CAT: I016980) is a heterobifunctional polyethylene glycol (PEG) linker featuring a tosyl (tosylate) leaving group on one end and a Boc-protected amine on the other, connected by a six-unit PEG spacer with a terminal methylene extension. The tosyl group enables efficient nucleophilic substitution with amines, thiols, or alkoxides, while the Boc-protected amine provides an orthogonal site for deprotection and downstream conjugation. The PEG6 backbone enhances solubility, flexibility, and hydrophilicity, reducing steric hindrance in bioconjugation reactions. Tos-PEG6-CH2-Boc is widely used in drug delivery, PROTAC synthesis, polymer chemistry, and biomaterials research, where dual reactivity and extended linker length are advantageous.
| CAS Number | 1530777-90-2 |
| Synonyms | tert-butyl 2-[2-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetate |
| Molecular Formula | C25H42O11S |
| Purity | ≥95% |
| IUPAC Name | tert-butyl 2-[2-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetate |
| InChI | InChI=1S/C25H42O11S/c1-22-5-7-23(8-6-22)37(27,28)35-20-19-33-16-15-31-12-11-29-9-10-30-13-14-32-17-18-34-21-24(26)36-25(2,3)4/h5-8H,9-21H2,1-4H3 |
| InChIKey | OIPLDSHYHFUPLX-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCC(=O)OC(C)(C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
