For research use only. Not for therapeutic Use.
Toosendanin（Cat No.:R016213）is a triterpenoid compound derived from the bark of Melia toosendan and related plants in the Meliaceae family. Traditionally used in Chinese medicine, it is known for insecticidal, antiparasitic, anti-inflammatory, and anticancer activities. Toosendanin induces apoptosis, inhibits tumor cell proliferation, and modulates pathways such as NF-κB and MAPK. It also exhibits neuroprotective and immunomodulatory effects, though its toxicity requires careful consideration in therapeutic use. With diverse pharmacological actions, Toosendanin remains a valuable natural compound for research in oncology, parasitology, and inflammatory disease treatment.
| CAS Number | 58812-37-6 |
| Synonyms | [(1S,2R,4R,5R,6S,8R,10S,11S,12R,14R,15R,16R,19S,21R)-4-acetyloxy-6-(furan-3-yl)-12,16,19-trihydroxy-5,11,15-trimethyl-3-oxo-9,17-dioxahexacyclo[13.3.3.01,14.02,11.05,10.08,10]henicosan-21-yl] acetate |
| Molecular Formula | C30H38O11 |
| Purity | ≥95% |
| IUPAC Name | [(1S,2R,4R,5R,6S,8R,10S,11S,12R,14R,15R,16R,19S,21R)-4-acetyloxy-6-(furan-3-yl)-12,16,19-trihydroxy-5,11,15-trimethyl-3-oxo-9,17-dioxahexacyclo[13.3.3.01,14.02,11.05,10.08,10]henicosan-21-yl] acetate |
| InChI | InChI=1S/C30H38O11/c1-13(31)39-20-10-19(34)29-12-38-25(36)26(20,3)17(29)9-18(33)28(5)23(29)22(35)24(40-14(2)32)27(4)16(15-6-7-37-11-15)8-21-30(27,28)41-21/h6-7,11,16-21,23-25,33-34,36H,8-10,12H2,1-5H3/t16-,17-,18+,19-,20+,21+,23-,24-,25+,26+,27+,28+,29+,30+/m0/s1 |
| InChIKey | NAHTXVIXCMUDLF-RFNFAWMESA-N |
| SMILES | CC(=O)O[C@@H]1C[C@@H]([C@@]23CO[C@H]([C@@]1([C@@H]2C[C@H]([C@@]4([C@@H]3C(=O)[C@@H]([C@@]5([C@]46[C@H](O6)C[C@H]5C7=COC=C7)C)OC(=O)C)C)O)C)O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
