Togni Reagent II

• CAT Number: R042445
• CAS Number: 887144-94-7
• Molecular Formula: C8H4F3IO2
• Molecular Weight: 316.02
• Purity: ≥95%
• Synonyms: 1-(Trifluoromethyl)-1,2-benziodoxol-3(1H)-one
• Storage: -20°C
• IUPAC Name: 1-(trifluoromethyl)-1$l^{3}
• InChI: InChI=1S/C8H4F3IO2/c9-8(10,11)12-6-4-2-1-3-5(6)7(13)14-12/h1-4H
• InChIKey: XHEOXSQMBWJOKP-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(=O)OI2C(F)(F)F

Togni Reagent II（Cat No.:R042445）is a hypervalent iodine(III) compound widely used for electrophilic trifluoromethylation in organic synthesis. Featuring a benziodoxole core and a trifluoromethyl group, it serves as a stable, crystalline source of CF₃ radicals or cations under mild conditions. Togni Reagent II enables selective trifluoromethylation of a broad range of substrates, including alkenes, alkynes, aromatics, and heterocycles. Its utility in modifying drug-like molecules and improving metabolic stability makes it valuable in medicinal chemistry. This reagent is favored for its ease of handling, efficiency, and broad functional group tolerance.