For research use only. Not for therapeutic Use.
TNIK-IN-7(CAT: I040537) is a potent and selective inhibitor of Traf2- and Nck-interacting kinase (TNIK), a serine/threonine kinase critically involved in Wnt/β-catenin signaling and cancer cell proliferation. By targeting TNIK’s kinase activity, TNIK-IN-7 disrupts the transcriptional activation of Wnt target genes, making it especially valuable for studying colorectal and other Wnt-driven cancers. TNIK-IN-7 has shown strong efficacy in preclinical models by suppressing tumor growth and modulating oncogenic transcriptional programs. It serves as a powerful research tool for investigating TNIK’s role in tumorigenesis, stemness, and therapeutic resistance. Suitable for in vitro assays and preclinical evaluations of Wnt pathway inhibitors.
| CAS Number | 1417795-24-4 |
| Synonyms | 4-methoxy-3-[2-(4-morpholin-4-ylanilino)pyridin-4-yl]benzonitrile |
| Molecular Formula | C23H22N4O2 |
| Purity | ≥95% |
| IUPAC Name | 4-methoxy-3-[2-(4-morpholin-4-ylanilino)pyridin-4-yl]benzonitrile |
| InChI | InChI=1S/C23H22N4O2/c1-28-22-7-2-17(16-24)14-21(22)18-8-9-25-23(15-18)26-19-3-5-20(6-4-19)27-10-12-29-13-11-27/h2-9,14-15H,10-13H2,1H3,(H,25,26) |
| InChIKey | FOWKPAQNTXMWQQ-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C(C=C1)C#N)C2=CC(=NC=C2)NC3=CC=C(C=C3)N4CCOCC4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
